Fig. 2. Functional enrichment of miR-181b-5p and miR-330-3p. Top five categories according to (A) REACTOME: Regulation of phosphatase and tensin homolog (PTEN) gene transcription, extracellular matrix organization, diseases of glycosylation, phosphatidylinositol-3,4,5-triphosphate (PIP3) activates protein kinase B (AKT) signalling, and PTEN regulation; and (B) Kyoto Encyclopaedia of Genes and Genomes (KEGG): microRNAs in cancer, cellular senescence, mitophagy—animal, cell cycle, and endocrine resistance. FDR, false discovery rate.
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