Fig. 1. The immune profile, fibrosis, and senescence in adipocytes and triple-negative breast cancer (TNBC). The similarities between the tumor microenvironment in TNBC and obesity and their effects on the development of cancer. Natural killer (NK), natural killer T (NKT) cells, and lymphocytes indicate modification of the immune network, fibroblast and collagen participate in the facilitation of fibrosis, and senescent cells and senescence-associated secretory phenotype are related to initiation of senescence.
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