Fig. 1. (A) PanCancer and (B) a custom panel were used to assess whole-blood gene expression. Gene counts above background are represented in logFC2 volcano plots with expression relative to the healthy control. Genes with significant differential expression between groups are represented by red dots, all other genes are represented by black dots. Four genes showed similar expression differences in the two panels and are labelled with the gene name: (C) C-X-C motif chemokine receptor 6 (CXCR6), (D) cathelicidin antimicrobial peptide (CAMP), (E) lipocalin 2 (LCN2), and (F) lactotransferrin (LTF). Circles and triangles are used to differentiate the two groups. Data are expressed as mean± standard deviation. Significant difference based on *Student’s t-test (P<0.001); †Mann-Whitney test (P<0.001); ‡Mann-Whitney test (P<0.0001). FC, fold change; MetDys, metabolic dysregulation.
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