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Fig. 1. Relationship between body fat mass and frequency of type 2 diabetes mellitus (T2DM). Background data were extracted from 1,650 participants of the Leipzig Obesity BioBank9 that represent a wide range of age (18 to 96 years), body mass index (16 to 92 kg/m²), and body fat mass (7.5% to 60%) from among people with lipodystrophy to morbid obesity.14 For categories of 2.5% or 5% body fat mass groups, the prevalence T2DM is displayed. The j-curved extrapolated line does not represent the exact mathematical relationship, but the hypothetical curve suggests that both severely low fat mass in people with lipodystrophy and obesity are associated with a higher risk of developing T2DM.
J Obes Metab Syndr 2024;33:275~288 https://doi.org/10.7570/jomes24013
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