Adverse events (AEs) of lorcaserin
| Authors | Number of subjects | Duration (months) | Serious AEs | Serious AEs assessed as possibly related to drug | |
| Smith et al. (2010)3 (BLOOM) | 3,182 | 24 | Headache | Cardiac disorder (2) | |
| Upper respiratory infection | Gastrointestinal disorder (4) | ||||
| Dizziness | General disorder (2) | ||||
| Nausea | Hepatobiliary disorder (6) | ||||
| Constipation | Immune system disorder (1) | ||||
| Fatigue | Infection (7) | ||||
| Dry mouth | Injury and poisoning (6) Metabolism | ||||
| Abnormal laboratory test (1) | |||||
| Metabolism disorder (1) | |||||
| Musculoskeletal disorder (8) | |||||
| Neoplasm (6) | |||||
| Nervous system disorder (4) | |||||
| Psychiatric disorder (1) | |||||
| Reproductive system or breast disorder (8) | |||||
| Respiratory disorder (3) | |||||
| Fidler et al. (2011)20 (BLOSSOM) | 4,008 | 12 | Headache | (76) | Syncope (1) |
| Upper respiratory infection | Moderate depression (1) | ||||
| Nausea | Acute anxiety attack (1) | ||||
| Dizziness | |||||
| Fatigue | |||||
| O'Neil et al. (2012)21 (BLOOM-DM) | 604 diabetic patients | 12 | Headache | 6.3% (10 mg BID) | |
| Back pain | 8.4% (10 mg QD) | ||||
| Nasopharyngitis | |||||
| Nausea | |||||
| Urinary tract infection | |||||
| Cough | |||||
| Symptomatic hypoglycemia | |||||
| Fatigue | |||||
| Gastroenteritis | |||||
| Dizziness | |||||
| Influenza | |||||
| Procedural pain | |||||
| Hypertension | |||||
| Depression |
Occurred at a rate of ≥5% in any treatment group and more frequently than in placebo group (