Table. 3.

Metabolic effects on lipid profiles after one year of dapagliflozin treatment

Group ΔTotal cholesterol (mg/dL) ΔTG (mg/dL) ΔHDL-C (mg/dL) ΔLCL-C (mg/dL) ΔNon-HDL-C (mg/dL)
Total 0.71±27.2 -4.4±56.5 2.4±7.7 -2.4±25.2 -1.7±27.0
Group 1+2+3 P=0.093 P=0.200 P=0.068 P=0.366 P=0.289
Group 1 -1.3±32.1 -0.25±57.9 5.0±15.4 -4.4±27.8 -10.5±56.7
 (Dual combination) P=0.405 P=0.541 P=0.307 P=0.541 P=0.286
Group 2 -3.58±24.9 -7.8±65.8 3.5±9.3 -10.4±17.6 -7.1±19.3
 (Triple combination) P=0.774 P=0.146 P=0.388 P=0.388 P=0.774
Group 3 -0.36±25.3 -6.8±52.5 1.64±6.5 1.24±24.0 -2.0±26.2
 (Quadriple combination) P=0.424 P=0.424 P=0.405 P=0.307 P=0.678

Values are presented as mean±standard deviation.

Δ, difference in values before and after one year of treatment; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.

J Obes Metab Syndr 2017;26:107~113 https://doi.org/10.7570/jomes.2017.26.2.107
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