Study flow. We analyzed data from 61 patients who underwent a minimum of 12 months of dapagliflozin therapy (10 mg once-daily) and who visited Sejong General Hospital between January 2015 and July 2016. Patients were selected according to the following inclusion criteria: age between 18-75 years and type 2 DM. Patients were excluded if they took dapagliflozin for less than 12 months; their therapy was combined with an insulin or GLP-1 agonist; they had type 1 DM, GDM, or MODY; they were an active cancer patient; or were lost to follow-up. Patients were assigned to one of three ongoing dapagliflozin+ treatment regimens: group 1) metformin; group 2) metformin with sulfonylurea or dipeptidyl-peptidase IV (DPP-4) inhibitors; group 3) metformin and sulfonylurea with dipeptidyl peptidase IV (DPP-4) inhibitors (Group 3). GLP-1, glucagon like peptide-1; GDM, gestational diabetes mellitus; MODY, maturity onset diabetes of the young; MFM, metformin; SU, sulfonylureas; DPP-IV I, dipeptidyl peptidase IV inhibitors.