Fig. 6. Water extract of Artemisia annua (WEAA) affects the biochemical index of high-fat diet (HFD)-induced obesity in Sprague Dawley (SD) rats. SD rats were orally administered WEAA (200 mg/kg) or water once a day for 7 weeks. SD rats were fed a normal diet or a 60% HFD during the experimental period. The experimental groups are as follows: (1) SD vehicle group with a normal diet (ND+water, n= 9); (2) SD vehicle group with a HFD (HFD+water, n= 9); and (3) SD rats with a HFD+200 mg/kg WEAA group (HFD+WEAA, n= 9). After the animal was anesthetized with isoflurane, blood was collected and centrifuged at 3,000 rpm for 10 minutes. Serum was analyzed for (A) high-density lipoprotein (HDL) cholesterol, (B) low-density lipoprotein (LDL) cholesterol, and (C) total cholesterol (TC), as well as (D) triglyceride (TG), (E) alanine aminotransferase (ALT), and (F) aspartate aminotransferase (AST). Values are presented as mean± standard deviation. One-way analysis of variance followed by Dunnett post-test was performed for statistical analysis. *P < 0.05; †P < 0.01; ‡P < 0.001.
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