Fig. 3. Infiltrated macrophages and crown-like structures in white adipose tissue (WAT). Arrows indicate infiltrated macrophages and crown-like structures found in WAT of obese mice. Hypertrophic adipocytes undergo necrosis due to lack of nutrients and oxygen, and the infiltrated macrophages surround dead adipocytes. Visceral WAT dissected from obese mice was sectioned and stained with H&E.
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