Journal of Obesity & Metabolic Syndrome

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J Korean Soc Study Obes 2000; 9(2): 122-127

Published online July 1, 2000

Copyright © Korean Society for the Study of Obesity.

Effect of Obesity on BMD in Postmenopausal Women

Han Jin Oh1,Chang Hoon Lim,Ho Yeon Chung,Ki Ok Han,Hak Chul Chang,Hyun Koo Yoon,In Kwon Han

Dept. of Family Medicine1, Internal Medicine, Samsung Cheil Hospital, Sungkyunkwan University, School of Medicine, Seoul, Korea

Abstract

In postmenopausal women, it has been noted that heavier women conserve bone better than
those with lower body weight. The protective effect of obesity on bone mass has been ascribed
to a high body fat content. The present study of 123 postmenopausal women was undertaken to
determine the effects of obesity on sex hormone, FSH, SHBG, and BMD at lumbar spine of
Korean postmenopausal women. Our result revealed that obese group has greater bone mineral
density at lumbar spine than non-obese group. But, obese group was noted that have lower levels
of FSH and SHBG than non-obese group significantly. But, we couldnt find out the
differentiation of levels of estradiol between two groups. Age adjusted values for BMD at lumbar
spine, respectively, were positively correlated (r=0.219, p<0.05) with BMI. And levels of FSH,
adjusted with age, also revealed that have negative correlation (r=-0.243, p<0.05) with BMI. So,
we concluded that the protective effect of obesity on bone is related with FSH and SHBG, not
with estradiol.

Keywords: Obesity, Postmenopausal women, BMD, SHBG, Estradiol