J Korean Soc Study Obes 2002; 11(2): 131-141
Published online June 1, 2002
Copyright © Korean Society for the Study of Obesity.
Lee Bok-Gi M.D.,Lee Kyu-Rae M.D.1,Song Mi Kyung Ph.D.,Park Mi-Hyun Ph.D.,Hwang Sung Joo M.D.2
Bariatric Medicine, Charm Clinic, Seoul1, Research and Development center, Erom Life Ltd., Seoul2
Background: Among the obese and those
interested in weight reduction, the use of meal
replacements recently has gained popularity. The
efficacy and safety of meal replacements, however,
has been questioned. In addition, the imprudent use
of meal replacements lead to significant economic
costs. Therefore, this study will investigate the
efficacy and safety of meal replacements by
examining obese women who take meal replacements.
Methods: This experiment was conducted with
subjects who volunteered through the internet and
the mass media. The duration of the experiment was
six weeks. The subjects consisted of 54 obese
women (BMI>25) whose ages ranged from 25 to
35.54 subjects were divided into two groups: Group
A, the experimental group, took meal replacements
for breakfast and dinner. Group B, the control group,
received instruction concerning exercises and diets.
Anthropometric measurement, body composition and
metabolic variations were evaluated the first day, the
third week and the sixth week; in addition, the
subjects' diet diaries were analyzed.
Results: 42 out of 54 finished the six weeks
experiments. 35 out of the 42 completed diet diaries.
The results are based on the 35 subjects' diet diaries.
Group A took 1042.61±179.73 kcal/day, and group B
took 1313.49±308.07 kcal/day for six weeks. This is
a statistically significant difference between two
Group A showed a significant reduction in weight
(-3.84±1.97 kg), the percentage of body fat (-1.42±
2.20%), and in waist and hip circumference. Group
B also showed a significant reduction in weight
(-3.39±2.25 kg) and in waist and the hip circumference.
In group A, there was a significant
reduction in the LDL cholesterol and in systolic and
diastolic blood pressure. In group B, there was a
significant reduction in total cholesterol, LDL
cholesterol and in systolic blood pressure.
There was no significant difference in changes of
weight and body fat between the two groups.
Conclusion: From these results, Korean women
who took meal replacements twice a day for six
weeks reduced their oral intake, weight and body fat.
However, long-term studies are needed to clarify the
comparison between two groups.
Keywords: Meal replacements