Journal of Obesity & Metabolic Syndrome



J Korean Soc Study Obes 2003; 12(3): 228-233

Published online September 1, 2003

Copyright © Korean Society for the Study of Obesity.

A Case of Gitelman's Syndrome in Obese Patient Taking Diuretics for the Purpose of Weight Reduction

Chul Sik Kim M.D.,Jin Hyuck Chang M.D.,Jina Park M.D.,Min Ho Cho M.D.,Joo Young Nam M.D.,Jong Suk Park M.D.,Dol Mi Kim M.D.,Chul Woo Ahn M.D.,Bong Soo Cha M.D.,Sung Kil Lim M.D.,Kyung Rae Kim M.D.,Hyun Chul Lee M.D,Soon Won Hong1 M.D.

Department of Internal Medicine, Department of Pathology1, Yongdong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea


Gitelman’s syndrome is a primary renal tubular disorder characterized by chronic hypokalemia, hypomagnesemia, metabolic alkalosis of renal origin, hypocalciuria with normocalcemia, hyperreninemic hyperaldosteronism, increased excretion of urinary prostaglandins and hyperplasia of juxtaglomerular pparatuson renal pathology. It is a rather benign condition not uncommonly detected in asymptomatic adults because of unexplained hypokalemia. This condition has been frequently mistaken for chronic dichlozid use. We have experienced a case of Gitelman’s syndrome in a 41-year old woman taking diuretics for the purpose of weight reduction.

Keywords: Gitelman´s syndrome, Diuretics, Weight reduction, Hypokalemia