Journal of Obesity & Metabolic Syndrome



Korean J Obes 2010; 19(1): 1-8

Published online March 1, 2010

Copyright © Korean Society for the Study of Obesity.

Omega-3 Index as a Risk Factor for Cardiovascular Disease and
Its Application to Korean Population

Yongsoon Park

Department of Food and Nutrition, Hanyang University


Of all known dietary factors, long-chain omega-3 fatty
acids (eicosapentaenoic acid and docosahexaenoic acid)
may be the most protective against death from
cardiovascular disease. Evidence continues to accrue for
benefits of omega-3 fatty acids in the prevention of
coronary heart disease and stroke. Anti-arrhythmogenic,
anti-inflammatory, anti-thrombotic and hypolipidemic
effects of omega-3-fatty acids are emerging as the most
likely explanation. New evidence has confirmed and
refined the cardioprotective risk factor of Omega-3 Index,
the only standardized blood test of omega-3 fatty acids
measuring content of erythrocyte eicosapentaenoic and
docosahexaenoic acids. Current evidence suggests that
individuals with coronary artery disease may reduce their
risk of sudden cardiac death by increasing their intake of
long-chain omega-3 fatty acids by approximately 1 g per
day and achieving a target range of 8-10% Omega-3
Index. However, target range of Omega-3 Index for
Koreans may be higher than 10%.

Keywords: Cardiovascular disease, Docosahexaenoic acid, Eicosapentaenoic acid, Inflammation, Lipoprotein, Omega-3 Index, Platelet