Korean J Obes 2011; 20(3): 147-159
Published online September 1, 2011
Copyright © Korean Society for the Study of Obesity.
Dong Hoon Lee†, Seung Hwan Lee†, Kiyong An, Jin Young Moon, So Hun Kim(1),
Yoon Jin Choi(1), Moonsuk Nam(1)*, Justin Y. Jeon*
Department of Sport and Leisure Studies, Yonsei University, Department of Internal Medicine, College of Medicine, Inha University(1)
Background: Although lifestyle modification has been recommended for Type 2 diabetic patients, little is known about the effect of combined exercise (aerobic and resistance training) on macrovascular complications and metabolic parameters. The purpose of this study was to investigate the effects of 6 weeks of lifestyle modification including combined exercise program on body composition, physical fitness, the risk of macrovascular complications and metabolic parameters in Type 2 diabetic patients.
Methods: Thirty-five patients with type 2 diabetes were selected as research participants from I-Hospital in Incheon Metropolitan City. Patients were randomized into a lifestyle modification group (n = 23) and a control group (n = 12). Six weeks of lifestyle modification included supervised core and circuit resistance exercise (3 times/week), unsupervised aerobic exercise (2~3 times/week) and diet counseling (once a week) by clinical nutritionist. Body composition, blood pressure, physical
fitness, macrovascular complications risk (baPWV, ABI), metabolic parameters including glucose, insulin, homeostasis of insulin resistance (HOMA-IR), HbA1c, total cholesterol (TC), Gamma Glutamyl Transferase (GGT) were measured before and after the intervention.
Results: After the 6 weeks of lifestyle modification, the significant improvements were found in body
composition and overall physical fitness levels (P < .05), whereas HbA1c, TC, GGT were significantly decreased after the intervention (P < .05). Further multiple regression analysis showed the changes in lean mass, VO2max were predictors for changes in HbA1c levels after the lifestyle
modification. On the other hand, arterial stiffness was not significantly changed but maintained.
Conclusion: Lifestyle modification including combined exercise program had beneficial effects on body composition, physical fitness, glycemic control, metabolic parameters in Type 2 diabetic patients. Moreover, combined exercise including resistance training did not show any side-effects and maintained the level of arterial stiffness.
Keywords: Arterial stiffness, HbA1c, Diabetes, Combined exercise, Lifestyle modification