Korean J Obes 2014; 23(4): 236-241
Published online December 30, 2014
Copyright © Korean Society for the Study of Obesity.
Chan-Hee Jung, Ji-Oh Mok*
Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Vitamin D affects not only musculoskeletal health but also a range of nonskeletal diseases such as cancer, obesity, metabolic syndrome, type 2 diabetes and cardiovascular disease. Vitamin D deficiency and obesity have been recognized as pandemic diseases with much health consequences. The ‘cause-effect’ relationship of vitamin D to obesity has been the area of much recent activity. There is consistent association in the published literature between higher body mass index (BMI) and lower 25-hydroxyvitamin D (25(OH)D) concentrations, but the mechanisms are not fully understood. Although recent studies suggest that low serum vitamin D is the consequence of obesity, the results from randomized controlled trials are still scarce and inconclusive to establish the relationship between vitamin D and obesity. Moreover, the role of vitamin D in the pathophysiology of obesity is still debatable and there is little evidence for a direct effect of vitamin D supplementation on body weight. Therefore, randomized large-scale double-blind controlled trials are needed in the future to clearly establish the effects of vitamin D in obesity.
Keywords: Vitamin D, Obesity