Journal of Obesity & Metabolic Syndrome



J Korean Soc Study Obes 1997; 6(1): 67-73

Published online June 30, 1997

Copyright © Korean Society for the Study of Obesity.

A Study of Effect of Low Calorie High Protein Diet on Weight & Health Risk Reduction

Nam Han Cho*, Duck Joo Lee**, Sang Man Kim**, Eun Ju Lee***

Department of Preventive Medicine*, Family Practice and Community Medicine**, Dianostic Radiology*** School in Medicine, Ajou University, Suwon, Korea


It is well known that obesity is significantly associated with chronic diseases such as cardiovascular disease, hypertension, and diabetes. However, a existing methods to reduce the level of obesity is not simple and premature. Diet, exercise, and use of weight reducing drugs are widely used as the methods of weight loss, but these methods are frequently coexist with the side effects or regain of weight. Therefore, this study under went to evaluated the high protein-low calorie dietary food(Balance) as another method of weight loss. Specifically, we evaluated change of weight, body mass index, waist-hip ratio, body fat content, the lipid profiles, kidney function, liver function, thyroid, change of sex hormone, and glucose metabolism.
A total of 61 women were recruited from Ajou university comprehensive health center and Ajou university medical complex(ie, hospital and medical school). Subjects with any type of metabolic diseases such as, chronic diseases, cardiovascular disease, diabetes, liver diseases and cancer were excluded from the study. Beginning of the study, participant’s diet, family history, and history of weight change were evaluated by the trained interviewer. We asked the participants to wear light clothing during the weight and height measurement. Fasting, more than 8 hours, blood was drawn to evaluate any metabolic indices.
Study participants mean age was 35.6 years old(youngest was 18 years and oldest 57 years old). Approximately 70% of the participants have had their obesity and other risk factors measured more than a two occasions. No significant effects of Balance on most of the study variables were observed during the follow-up period of 7 to 145 days. However, we observed significant difference on total cholesterol, body fat and fasting glucose level after Balance use. The mean weight was changed approximately 5%(P < 0.001), 73.4 kg to 69.9 kg, during 66 days of the treatment. Furthermore, we observed subjects with 2 kg weight gain to maximum of 14.2 kg reduction. Although, it is not statistically significant, we observed the mean of 3cm reduction in waist-hip ratio. On the other hand, the BMI was significantly(P < 0.001) reduced from 29.3 to 27.9. We further analyzed the effects of Balance among the three age groups(< 30 yrs, 30~39 yrs, and > 40 yrs). We found similar pattern and magnitude of weight change among the three groups. However, the pattern was somewhat different in waist-hip ratio. In older group(> 40 yrs), waist-hip ratio declined in the beginning of the treatment but returned to the initial level. However, in the other two groups(< 30 yrs, and 30~39 yrs), waist-hip ratio declined persistently from the beginning of the treatment. Although, weight and BMI was inversely correlated with participant’s age but it was not significantly affecting on change of either weight or BMI.
In conclusion, we observed a positive effect of high protein low calorie diet food on the reduction of weight, body fat, total cholesterol and glucose. However, one should be cautious with the high protein diet which subsequently increase in formation of ketone body and possibly results in dehydration. And low caloric diet also reduce in energy expenditure, thus to prevent this phenomenon we suggest that low caloric diet should be combined with an exercise to maximize and maintain weight loss.

Keywords: High protein low callorie diet food, Obesity, Diet