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Korean J Obes 2013; 22(2): 107-113

Published online June 30, 2013

Copyright © Korean Society for the Study of Obesity.

The Relationship Between Brain-derived Neurotrophic Factor, Serotonin, Physical Fitness, Energy Expenditure and Exercise Intensity in Children

Hyun-Jun Kim*

Department of Physical Education, Kyungnam University

Received: February 7, 2013; Reviewed : February 22, 2013; Accepted: April 23, 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Background: The purpose of this study was to determine the effects of physical activity and fitness on brain nerve growth factor in children.
Method: Seventy-three subjects were selected from one elementary school. Variables related to physical fitness, physical activity and brain nerve growth were measured and assessed. The physical activities of daily life were measured using the SenseWear Armband (Bodymedia Co., USA). The collected data were analyzed in terms of Total energy expenditure, average METs, duration of activity less than 3.0 METs, duration of activity between 3.0 and 5.9 METs, and duration of activity exceeding 6 METs. The factors of brain nerve growth factor were BDNF (brain-derived neurotrophic factor) and serotonin. Data analysis was done using PASW Statistics 18.0 program and included Pearson correlation coefficients and stepwise regression analysis.
Results: Positive correlation was found between BDNF and duration of activity exceeding 6 METs. Negative correlation was noted between BDNF and muscular strength, also between serotonin and muscular strength. The independent variables predicting BDNF were agility, muscular strength, duration of activity exceeding 6 METs and duration of activity less than 3.0 METs. And predictor
of serotonin was muscular strength.
Conclusion: The results indicate that in order to increase BDNF and serotonin in children, it is necessary to improve agility and muscular strength, increase duration of activities less than 3.0 METs and exceeding 6 METs.

Keywords: BDNF, Serotonin, Physical fitness, Energy expenditure, Exercise intensity


The characteristics of participants



The correlation between variables (n = 73)



The effect of physical fitness and activity on BDNF (n = 73)



The effect of physical fitness and activity on Serotonin (n = 73)


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