J Obes Metab Syndr 2019; 28(4): 295-296
Published online December 30, 2019 https://doi.org/10.7570/jomes.2019.28.4.295
Copyright © Korean Society for the Study of Obesity.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea
Correspondence to:
Ji A Seo
https://orcid.org/0000-0002-1927-2618
Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, 123 Jeokgeum-ro, Danwon-gu, Ansan 15355, Korea
Tel: +82-31-412-4275 Fax: +82-31-412-5984 E-mail: seojia@korea.ac.kr
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Recent consensus reports are emphasizing that reduced muscle strength (dynapenia) and poor physical performance are key diagnostic criteria of sarcopenia, as much as loss of muscle mass is, although definitions vary.1,2 Aging is a universal cause of decreased muscle mass and strength. However, in addition to aging, many chronic diseases including diabetes mellitus (DM) can accelerate loss of muscle mass and strength. Dynapenia was found to be associated with an increased risk of all-cause and cardiovascular mortality in many studies3,4 but somewhat controversial in a prospective study of diabetics.4
In the issue of the
First, comparative data are needed to confirm that the characteristics of obese and nonobese people were similar. A longer duration of diabetes and higher concentrations of glucose and insulin are associated with accelerated muscle loss7 and disability.8 If nonobese DM subjects had more severe hyperglycemia than obese DM subjects, a more pronounced association with DM could be seen in nonobese subjects. In addition to the severity of DM, insufficient protein intake could also be an important factor. Second, to confirm the results, a stratified analysis of obesity based on a non-BMI basis (e.g., body fat percent, waist circumference, etc.) would be useful. In addition, the percentage of blue-collar workers and socioeconomic status distribution could be considered confounding.
Nevertheless, this study added another piece of evidence to our understanding of the relationship between low muscle strength and DM using a nationally representative sample of adults in Korea. Low muscle mass increases the risk of developing type 2 DM in Koreans.9 Future prospective studies will be needed to assess the effects of body components, including muscle mass and fat deposition, and changes in the quality and function of muscles on the occurrence of DM and the development of diabetic complications.
The author declares no conflict of interest.
Online ISSN : 2508-7576Print ISSN : 2508-6235
© Korean Society for the Study of Obesity.
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