The Relationship of Central Obesity to the Risk of Complicated Diverticulitis

Sung Yeon Lee; Ji Suk Han; Rul Bin Kim; Ho Joong Kim; Sung Hoon Yu; Chul Sik Kim; Seong Jin Lee; Sung-Hee Ihm; Choong Kee Park; Kyo-Sang Yoo; Min-Jeong Kim; Jun Goo Kang

Article

Korean J Obes 2012; 21(4): 245-251

Published online December 30, 2012

The Relationship of Central Obesity to the Risk of Complicated Diverticulitis

Sung Yeon Lee, Ji Suk Han, Rul Bin Kim, Ho Joong Kim, Sung Hoon Yu, Chul Sik Kim, Seong Jin Lee, Sung-Hee Ihm, Choong Kee Park, Kyo-Sang Yoo⁽¹⁾, Min-Jeong Kim⁽²⁾, Jun Goo Kang^*

Author Affiliations

Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Department of Internal Medicine, Hanyang University Guri Hospital⁽¹⁾, Department of Radiology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine⁽²⁾

Received: September 3, 2012; Reviewed : October 5, 2012; Accepted: November 7, 2012

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

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Background: Predictive factors of severe diverticulitis are known to be sex, obesity, immunodeficiency and old age. However, the association between obesity and complicated diverticulitis is yet to be defined. We conducted the present study to clarify the association of central obesity with the risk of complicated diverticulitis.
Methods: A total of 117 patients were selected, who were diagnosed with colonic diverticulitis by abdominal CT from January 2005 to May 2007 at the authors’ institution.
For measuring obesity, body mass index (BMI) was calculated and the visceral fat area (VFA), subcutaneous fat area (SFA), total fat area (TFA) and abdominal circumference(AC) were determined from CT images. All parameters were analyzed using univariate statistics and multivariate logistic regression models.
Results: Out of the 117 patients with colonic diverticulitis, 111 (94.9%) cases involved the proximal colon. In 30 patients with complicated diverticulitis, 21 cases involved abscess formations and 9 cases showed perforated diverticulitis. Univariate analysis identified age, male sex, VFA, VFA/TFA
and AC as risk factors associated with complicated diverticulitis (P < 0.05). However, after adjusting for age and sex, none of the parameters showed increased risk for complicated diverticulitis.
Conclusions: Central obesity may not be a risk factor for increasing the risk of complicated colon diverticulitis in the Korean population.

Keywords: Diverticulitis, Complication, Visceral obesity, BMI

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Fig. 1. Measurement of total and visceral fat area of Haunsfield number -175~-25 at the umbilicus level. (A) Measurement of total fat area, (B) Measurement of visceral fat area.

Tables

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Baseline characteristics of the study population

A comparison of the mean differences in risk factors of simple and complicated diverticulitis groups

Age- and sex-adjusted OR for the risk of complicated diverticulitis

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