The Relationship Between Serum Magnesium Levels and Metabolic Syndrome in Korean Adults

In Jo Song; Chang-Hae Park; Won Chul Uh; Jung Yoon Yang; Jeongseob Lee; Seung Hwan Lee; Hyuk Ga

Article

Korean J Obes 2012; 21(1): 11-17

Published online March 30, 2012

The Relationship Between Serum Magnesium Levels and Metabolic Syndrome in Korean Adults

In Jo Song⁽¹⁾, Chang-Hae Park^(1).(2)*, Won Chul Uh⁽¹⁾, Jung Yoon Yang⁽¹⁾, Jeongseob Lee⁽¹⁾, Seung Hwan Lee⁽³⁾, Hyuk Ga⁽⁴⁾

Author Affiliations

Department of Family Medicine, College of Medicine, Eulji University⁽¹⁾, Department of Preventive Medicine, College of Medicine, Chungbuk National University⁽²⁾, Department of Family Medicine, College of Medicine, Korea University⁽³⁾, Institute of Geriatric Medicine, Eun-Hye Hospital⁽⁴⁾

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Background: Metabolic syndrome is a risk factor of cardiovascular diseases. Previous studies have reported that low serum magnesium levels are related to high blood pressure, diabetes mellitus and dyslipidemia. However, there have been few studies on association between serum magnesium levels and metabolic syndrome. Therefore, we investigated the relationship between them in this study.
Methods: This study was a cross sectional study including 524 Korean adults who visited a health promotion center in a university hospital from January 2010 to May 2011. Metabolic syndrome was defined according to the criteria of the American Heart Association. Multiple logistic regression analysis was used to evaluate the association between serum magnesium levels and metabolic syndrome, according to the lowest serum magnesium level group (1.8~2.0 mg/dL), the intermediate serum magnesium level group (2.1~2.2 mg/dL) and the highest serum magnesium level group (2.3~2.8 mg/dL).
Results: Compared with the highest serum magnesium level group, the odds ratio for metabolic syndrome in the lowest serum magnesium level group was 3.78 (95% CI = 1.48-9.69), and in the intermediate serum magnesium level group was 1.53 (95% CI = 0.63-3.70). Among the components
of metabolic syndrome, the odds ratios for abdominal obesity and hyperglycemia in the lowest serum magnesium level group were 5.48 (95% CI = 2.07-14.47), 2.41 (95% CI= 0.98~5.89) and for intermediate serum magnesium level group were 3.12 (95% CI = 1.25~7.78), 0.99 (95% CI =0.40~2.43), respectively.
Conclusions: A significant association was found between low serum magnesium levels and metabolic syndrome in Korean adults.

Keywords: Magnesium, Metabolic syndrome, Obesity, Diabetes mellitus, Hypertension, Dyslipidemia

Tables

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Characteristics of the subjects, according to the Tertile of magnesium levels

Pearson correlation coefficient between serum magnesium levels and characteristics of the target population

Forward stepwise multiple logistic regression analysis between serum magnesium and metabolic syndrome and its components.

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